There is no way to remove clothing from the closet once added, however in Chapter 11 when Villa Scaletta is burned down, everything but DLC clothing will be permanently removed. You can also purchase duplicate outfits, but only one will show in the closet. Purchased outfits may not be immediately available in the closet until a save point is reached in the game. There are also five different DLC packs that include additional clothing as well as Vehicles.
Once purchased or stolen from the store, your clothing will be stored in the closet of your safehouse to change into at your convenience. Aside from your appearance, changing clothing can help you lose your wanted status and even earn you achievements.
The Clothing in Mafia II offers the player many options to chose from, everything from a simple shirt and trousers to tailored three piece suits can be purchased from the games two clothing stores, Dipton Apparel and Vangel's.